Abstract Background d-3-phosphoglycerate dehydrogenase (PHGDH), which encodes the first enzyme in serine biosynthesis, is overexpressed in human cancers and has been proposed as a drug target.However, whether PHGDH is critical for the proliferation or homeostasis of tissues following the postnatal period is unknown.Methods To study PHGDH inhibition
Skeletal structure of Kura bleak, Alburnus filippii (Kessler, 1877), in South Caspian Sea basin
Kura bleak, Alburnus filippii, a member of the family Cyprinidae, is found in the Console Wire rivers of Aras and Sefidrud, and the Anzali lagoon of Iran.The current study was conducted to provide a detailed osteological description of this sp-ecies since there was not adequate information in this regard.In order to attain this goal, 20 specimens w
Investigating Claims of Eroticism in Images of the Annunciation
The usefulness of religious images to the Christian 2.5/3.5/6.5mm Cables Church in late-medieval Europe had long been appreciated, but their function was most clearly expressed from the time of Thomas Aquinas (1225-74) onwards.Images were to instruct the illiterate and the ignorant, to remind devotees about the mysteries of the faith by reference t
Living with Data: Aligning Data Studies and Data Activism Through a Focus on Everyday Experiences of Datafication
In this paper I argue that there is an urgent need for more empirical research into everyday experiences of living with datafication, something that has not been prioritised in the emerging field of data studies to date.As a result of this absence, the knowledge produced within data studies is not as aligned to the aims of data Bike Parts - Chainri